does methotrexate inhibit folic acid synthesis or Thymidylate synthase?

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Biology

does methotrexate inhibit folic acid synthesis or Thymidylatesynthase?

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Answer According to the given question Methotrexate is work as antagonist of folate Methotrexate responsible forinhibiting the enzyme DHFR or dihydrofolate reductase catalyzes the reduction of folic acid into tetrahydrofolic    See Answer
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