Discuss the structure and function of the juxtaglomerular
apparatus. What factors determine GFR? Why is it...
50.1K
Verified Solution
Link Copied!
Question
Medical Sciences
Discuss the structure and function of the juxtaglomerularapparatus. What factors determine GFR? Why is it so important tokeep GFR stable? Explain in terms of nephron function. Brieflydescribe the autoregulatory mechanisms used in the kidney tomaintain GFR on an ongoing basis.
Answer & Explanation
Solved by verified expert
3.6 Ratings (447 Votes)
Juxtamedullary apparatus maintains the filtration rate in the kidneys It is also involved in blood pressure regulation as well It mainly contains thick ascending limb macula densa the afferent arteriole that bring blood to the kidneys This apparatus is located near the glomerulus at the vascular pole The Macula densa is an epithelial layer that senses the sodium levels in the kidney filtrate that enters the tubule When there are high concentration of sodium detected the macula densa well cause efferent arteriole smooth muscle contraction in order to reduce blood flow to the glomerulus This will reduce the glomerular filtration rate GFR The juxtamedullary cells present in the glomerulus also secrete renin to increase blood pressure The juxtamedullary cells also have the lacis cells extraglomerular mesangial cells that are long elongated cells The lacis cells are located near the macula densa and have a presently unknown function Glomerular filtration rate is the rate at which the
See Answer
Get Answers to Unlimited Questions
Join us to gain access to millions of questions and expert answers. Enjoy exclusive benefits tailored just for you!
Membership Benefits:
Unlimited Question Access with detailed Answers
Zin AI - 3 Million Words
10 Dall-E 3 Images
20 Plot Generations
Conversation with Dialogue Memory
No Ads, Ever!
Access to Our Best AI Platform: Zin AI - Your personal assistant for all your inquiries!
