Discuss how nuclear hormone receptors work, and the diversity of their DNA targets, or response elements,...

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Biology

Discuss how nuclear hormone receptors work, and thediversity of their DNA targets, or response elements, andphysiological effects. Be specific.

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In the field of molecular biology nuclearreceptors are a class of proteins found within cells thatare responsible for sensing steroid and thyroid hormones andcertain other molecules In response these receptors work withother proteins to regulate the expression of specific genesthereby controlling the development homeostasis and metabolism ofthe organismNuclear receptors have the ability to directly bind to DNA andregulate the expression of adjacent genes hence these receptorsare classified as transcription factors The regulation of geneexpression by nuclear receptors generally only happens when aligand a molecule that affects the receptors behavior ispresent More specifically ligand binding to a nuclear receptorresults in a conformational change in the receptor which in turnactivates the receptor resulting in up or downregulation of geneexpressionA unique property of nuclear receptors that differentiates themfrom other classes of receptors is their ability to directlyinteract with and control the expression of genomic DNA As See Answer

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