Describe the submucosal plexus below. When it becomes activated
what is the major physiological response? When...
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Describe the submucosal plexus below. When it becomes activatedwhat is the major physiological response? When would this plexus beactivated?
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Submucous Plexus and the Control of Secretion Neurons in the submucous plexus of the intestine tend to be smaller than those in the myenteric plexus and contain fewer functional cell types Nevertheless the anatomical arrangement of the plexus is complicated with conflicting naming conventions The ganglia include multiple populations of secretomotor neurons projecting to the gut mucosa as well as vasodilator neurons innervating the local microcirculation Submucous ganglia also contain IPANs intrinsic primary afferent neurons with receptive endings projecting to the mucosa and with outputs to other submucous neurons or to the myenteric plexus About twothirds of submucosal neurons are likely to be cholinergic whilst both secretomotor and vasodilator neurons contain some combination of VIP and NOS Other submucous neurons contain 5HT substance P or somatostatin In the colon some neurons in the submucous plexus project to the deeper layers of the circular muscle These neurons are located closer to the circular muscle layer some contain NOS and VIP and are probably inhibitory Functions of other submucosal neurons projecting to the
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