Describe the selection process of alpha/beta T cells and use the following words in your description:...

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Biology

Describe the selection process of alpha/beta T cells and use thefollowing words in your description: lymphotactin, prothymocyte,double negative thymocyte, double positive thymocyte, singlepositive thymocyte, cortex, medulla, Hassall's corpuscles, postcapillary venule.

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Answer T cells are derived from haematopoietic stem cells that are found in the bone marrow The progenitors of these cells migrate to and colonise the thymus The developing progenitors within the thymus also known as thymocytes undergo a series of maturation steps that can be identified based on the expression of different cell surface markers The majority of cells in the thymus give rise to T cells however approximately 5 bear the T cell receptor TCR Developing thymocytes interact with the thymus stromal nonhaematopoietic cells and undergo the process described below in distinct regions of the thymus The thymus is made up See Answer

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