Describe the normal cellular functions of tumor suppressor genes and explain their roles in cancer. List all...

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Biology

Describe the normal cellularfunctions of tumor suppressor genes and explain their roles incancer. List all possible mechanisms by which tumor suppressorgenes are inactivated and explain. Explain whyloss-of-heterozygosity of a particular chromosome/chromosomalregion in tumor DNA suggests the existence of a tumor suppressorgene in that region.
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A Function tumour suppressor gene and role in cancer Tumour suppressor gene is antioncogene that regulates a cell division and replication The function of Tumor suppressor genes are Slow down cell division DNA repair Apoptosis or programmed cell death Role in cancer Tumor suppressor genes has the major function of apoptosis if the tumour suppressor genes are nonfunctional inactivated then it will affect apoptosis If there is no apoptosis then the cells will not die See Answer

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