Describe the eukaryotic RNAPII and contrast it to the prokaryotic RNAP. What additional elements are present...

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Biology

Describe the eukaryotic RNAPII and contrast it to theprokaryotic RNAP. What additional elements are present in RNAPII,and how do these contribute to transcription?

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Eukaryotic RNAPIIIt is a multiprotein complex It is an RNAP enzyme found in thenucleus of eukaryotic cells It catalyzes the transcription of DNAto synthesize precursors of mRNA and most snRNAand microRNAIt is a 550 kDa complexof 12 subunits RNA polymerase II is a main enzyme which catalysesDNAdirected mRNA synthesis during the transcription ofproteincoding genesPromoters In Eukaryotes promoters are the sequences which areimportant in the initiation of transcription of a gene Theinitiation of transcription in eukaryotes requires the enzyme RNApolymerase and transcription factors In eukaryotes thetranscription factors are mainly responsible for recognizingpromotersRNA polymeraseII promoter These promoters are variable in size and are several kilobasesupstream of transcription start site The core prmoter consists oftwo segments they are TATA box and Initiator or Inrsequenceslocated around nucleotide 1 Initiators are rich in pyrimidines some genes transcribed by RNA polymeraselI have only one of thesetwo components of the promoter core and some have none called nullgenes Besides TATA box and Inr which act as binding site forgeneral transcription factors other cis acting sequences act asbinding site for many See Answer

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