Logo
Home Study Material Contact Search
AI Chat FREE
  1. sciences
  2. biology
  3. describe the application of molecular testing to n

Describe the application of molecular testing to newborn screening for cystic fibrosis (CF)

50.1K

Verified Solution

Question

Biology

Describe the application of molecular testing to newbornscreening for cystic fibrosis (CF)

Answer & Explanation Solved by verified expert
4.0 Ratings (615 Votes)
CF is a relatively common autosomal recessive and frequently lethal condition caused by mutations in the CF transmembrane conductance regulator gene CFTR CFTR consists of 27 exons spanning approximately 250 kb on 7q3121 CFTR is a member of the ATPbinding cassette transporter family and encodes an anion transporter protein in the epithelium with five domains Two membranespanning domains form a chloride channel pore that plays a role in chlorine and bicarbonate transport and have secondary effects on sodium transport CFTR protein dysfunction leads to increased salt concentration in sweat and thickened secretions in various organ systems Numerous    See Answer
Get Answers to Unlimited Questions

Join us to gain access to millions of questions and expert answers. Enjoy exclusive benefits tailored just for you!

Membership Benefits:
  • Unlimited Question Access with detailed Answers
  • Zin AI - 3 Million Words
  • 10 Dall-E 3 Images
  • 20 Plot Generations
  • Conversation with Dialogue Memory
  • No Ads, Ever!
  • Access to Our Best AI Platform: Flex AI - Your personal assistant for all your inquiries!
Become a Member

Other questions asked by students

Finance
1.2K views

Payback, NPV, and IRR   Rieger International is evaluating the feasibility of investing ​$86 comma 00086,000 in a piece of...

Finance
1.2K views

An investment is expected to produce the following annual year-end cash flows: year 1: $5,000 year...

Biology
1.2K views

Suppose that an animal inhales a radioactive isotope of oxygen whose location can be traced in...

Basic Math
1.2K views

An airline owns an aging fleet of Boeing 737 jet airplanes. It is considering a major...

General Management
1.2K views

Can you please explain to me what is happening in the line Update PRODUCT 11QER/31, P_QTYOH from...

Physics
1.2K views

A charge of 90 nC is uniformly distributed along a rod of length L The...

Statistics
1.2K views

A scientist claims that in a population of fish at least 54 are female A...

Calculus
1.2K views

ndicate whether the table specifies a function Range 14 Domain 8 13 8 13 SEHEE...

Accounting
1.2K views

pls help Required information Use the following information for the Quick Study...

Accounting
1.2K views

In 2016, a company purchases securities at a cost of $225,000. Their year-end value is...

Finance
1.2K views

Commonwealth Construction (CC) needs $2 million of assets to get started, and it expects to...

Finance
1.2K views

Company Rich pays $2 in dividends annually and estimates that they will pay the dividends...