Describe in detail the CRISPR-Cas9 system of defense in bacterial against phages.

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Biology

Describe in detail the CRISPR-Cas9 system of defense inbacterial against phages.

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Clustered frequently interspaced brief palindromic repeats CRISPRs alongside Cas proteins is a prevalent program throughout bacteria as well as archaea which triggers interference against international nucleic acids The CRISPRCas structure functions in a minimum of 2 normal stages the adaptation phase the place that the cellular acquires brand new spacer sequences produced from international DNA so the interference phase that has the fairly recently acquired spacers to focus on as well as cleave invasive nucleic acid The CRISPRCas structure participates in a continuous evolutionary fight between bacteria and phages via deletion or addition of spacers in host cells as well as deletion or mutations found phage genomes This review describes the latest progress made in this fastexpanding field the acquisition of new spacer components appears to be a widespread microbial effect to avoid the picky pressure exerted by phage predation See Answer

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