Describe in detail the action of insulin. Be sure to include a description of what it...

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Medical Sciences

Describe in detail the action of insulin. Be sure toinclude a description of what it is (what kind of biomolecule/classof hormone), how its secretion is regulated, where specifically itis secreted from, its general effects on body cells, and finallyeach of its specific effects (if it has any) on: skeletal muscle,the liver, adipose tissue, and blood glucose levels.

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Structure of Insulin Insulin is a peptide hormone consisting of two chains A and B which are connected by disulfide bridges The molecular weight of insulin is 6000 1 The A chain contains 21 amino acids and B chain 30 amino acids 2 The final structure of insulin is determined by the Nterminal and Cterminal amino acids of A chain and the hydrophobic character of the amino acids at the Cterminal of B chain 3 However the hydrophobic character of the amino acids at the Cterminal of B chain is important for bio logical activity of insulin Secretion of Insulin Insulin secretion is greatly influenced by plasma glucose concentration Elevation of glucose level in plasma is an important stimulator of insulin secretion It is produced in the pancreas by the Islets of langerhans Regulation of Insulin Secretion Insulin secretion is mainly regulated by the feedback con trol signal provided by nutrients level in plasma When the nutrients are more insulin secretion increases to facilitate their metabolism and use and when nutrients are less insulin secretion is less Plasma Glucose Glucose is the most important stimulator of insulin secre tion With the rise in plasma glucose level there is almost a linear    See Answer
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