Depressed patients were randomly assigned to one of three groups: a placebo group, a group that...

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Depressed patients were randomly assigned to one of threegroups: a placebo group, a group that received a moderate dose ofthe drug, and a group that received a high dose of the drug. Afterfour weeks of treatment, the patients completed the Beck DepressionInventory. The higher the score, the more depressed thepatient.

We are now also interested if a patient's weight has an effecton the drug's effectiveness. Patients were categorized as eitherunderweight, overweight, or 'medium weight'.  Theserevised data are presented below. Use the Microsoft Excel \"AnovaSingle-Factor\" Data Analysis tool to conduct a 2-wayANOVA test for the data in the following table:

PlaceboModerate DoseHigh Dose
underweight422213
underweight521914
medweight413112
medweight412119
overweight39810
overweight33230
  1. What are your Fcrit values?
  2. If there is a significant difference between the weights, wherespecifically are the differences?
  3. Is there a significant interaction between weight and dosage?Why/why not?

Answer & Explanation Solved by verified expert
4.1 Ratings (807 Votes)

using excel>data >data analysis>two way anova

we have

Anova: Two-Factor With Replication
SUMMARY Placebo Moderate Dose High Dose Total
underweight
Count 2 2 2 6
Sum 94 41 27 162
Average 47 20.5 13.5 27
Variance 50 4.5 0.5 260.8
medweight
Count 2 2 2 6
Sum 82 52 31 165
Average 41 26 15.5 27.5
Variance 0 50 24.5 146.3
overweight
Count 2 2 2 6
Sum 72 31 10 113
Average 36 15.5 5 18.83333
Variance 18 112.5 50 234.9667
Total
Count 6 6 6
Sum 248 124 68
Average 41.33333 20.66667 11.33333
Variance 37.86667 55.46667 39.86667
ANOVA
Source of Variation SS df MS F P-value F crit
Factor A 284.1111 2 142.0556 4.124194 0.053546 4.256495
Factor B 2828.444 2 1414.222 41.05806 2.99E-05 4.256495
Interaction 71.88889 4 17.97222 0.521774 0.722608 3.633089
Within 310 9 34.44444
Total 3494.444 17
  1. Fcrit values are 4.257 and 3.633
  2. since p value of Factor B (weights) are less than 0.05 so we can say that there is a significant difference between the weights.
  3. NO there a not significant interaction between weight and dosage because p value is greater than 0.05

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