David, a 21-year-old male, demonstrated the following:
Poor muscle development, high-pitched voice, microphallis,eunuchoidism, anosmia, tall stature (6'7\")
Upon further questioning, it was found that David was born witha cleft palate, only one kidney and cryptorchidism.
A blood sample revealed low serum levels of FSH, LH andTestosterone.
2. What secondary sex characteristics is David lacking?
3. Name the endocrine disorder (be specific) in this case. Is thisa primary or secondary disorder?
4. Diagram the feedback loop involved.
5. Why is David suffering from anosmia?
6. How can David's tall stature be explained?
7. Can his condition be treated? If so, how?
8. Will he be able to father children if left untreated? Why or whynot?
9. Is this disorder genetic? If so, which chromosome is affected?Is this always the case?
