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Consider the following pedigree of an autosomal recessive disease named PKU Assume that the individuals...

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Consider the following pedigree of an autosomal recessive disease named PKU Assume that the individuals 111 115 III1 and II14 are all homozygous non affected P 1111 111 A 1112 11 fr 112 PP Pa 113 1113 B GP M N PP PP P T Yer M Plt P PP PC PP 114 Part 2 Assuming that the individuals 11 and 14 are both heterozygous Q PP 1114 Part 1 Assuming that the individuals 11 and 14 are homozygous 1 List all known genotypes of the family members PP PP So the PP PP PP 2 If persons A and B marry what is the probability that their first child will have PKU it will me Pp 14 PP 115 Prm 2 3 3 If the first child of A and B is normal what is the probability that their second child will have PKU The Polity 3 4 2 0 0 03 4 If the first child of A and B have the disease what is the probability that their second child will be then as the front of having 3 4 te to brag IS Be Perials M affected 5 List all known genotypes of the family members 6 If persons A and B marry what is the probability that their first child will have PKU 7 If the first child of A and B is normal what is the probability that their second child will have PKU 8 If the first child of A and B have the disease what is the probability that their second child will be affected

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