Compounds in the saliva, hair and urine of pets may potentially trigger asthma in some patients....

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Compounds in the saliva, hair andurine of pets may potentially trigger asthma in some patients. Totest this hypothesis, some researchers conducted a study. As testsubjects, they used 8 families, 4 of which had a pet in their homeand 4 did not. They measured respiratory flow of each familymember, as this is known to decrease in patients with asthma.Recent research has shown body weight to correlate with asthma inchildren, and sex, age, and height are also known to affectrespiratory flow measures. Therefore, the researchers measured andincluded these covariates in their model to control for anyconfounding effects that they may have had before testing theirtreatment of interest (whether the home had pets). The analysisconducted by the researchers is presented below. They concludedthat pets in the family do not influence respiratory flow.

>attach(pets.data)

> pets.data

resp.flow body.weight treatment sexage height family

1266          41    pet   F 13    130Smith

2400          95    pet    M 37   190   Smith

3369          81    pet    F 36   180   Smith

4365          78    pet    M 42   185   Wilson

5351          75    pet    M 35   192   Wilson

6334          62    pet    F 41   170   Taylor

...

13391         78         nopet   M 41    180 Singh

14340          62       no pet   F27    177 Singh

15337         55         nopet   F 34    185 Singh

16389         87         nopet   M 27    172 Campbell

17376         78         nopet   F 33    167 Campbell

18338         57         nopet   F 47    155 Li

19337         62         nopet   M 50    172 Li

20359         69         nopet   M 18    173 Li

>model<-lm(resp.flow~treatment+sex+age+height+body.weight)

>anova(model)

Analysis of Variance Table

Response: resp.flow

           Df Sum Sq Mean Sq F value   Pr(>F)   

Treatment   1    1.8     1.8  0.0569    0.8149   

sex          1 6626.96626.9 209.6419 8.117e-10 ***

age          1 10264.810264.8 324.7247 4.396e-11 ***

height       1 8346.9 8346.9 264.05361.758e-10 ***

body.weight 1 5786.0 5786.0 183.03731.978e-09 ***

Residuals   14  442.6   31.6                      

---

Signif. codes: 0 '***' 0.001 '**'0.01 '*' 0.05 '.' 0.1 ' ' 1

a) Identify threeaspects of the design and/or analysis of this study that reduceyour confidence in the conclusion that pets dont influencerespiratory flow.    

b) List fourassumptions of the model used in this analysis.

c) If the assumptions aren’t met,what are three approaches you can take to analysethe data?

d) Which variable in their analysisexplained the most variance in respiratory flow?

e) In the ANOVA table below, which letters (A-E) representnumbers that would NOT change if the sample size of peopleincreased?                    (1 mark)

Response: resp.flow

Df Sum Sq Mean Sq F valuePr(>F)   

Treatment   A           B            C           D                    E   

sex 1 6626.9 6626.9 209.64198.117e-10 ***

age 1 10264.8 10264.8 324.72474.396e-11 ***

height 1 8346.9 8346.9 264.05361.758e-10 ***

body.weight 1 5786.0 5786.0 183.03731.978e-09 ***

Residuals   14  442.6   31.6                      

       

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