Compare and contrast the different mechanisms for regulating differential gene expression. Predict different mechanisms that could be...

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Biology

Compare and contrast the different mechanisms for regulatingdifferential gene expression.
Predict different mechanisms that could be responsible forcontrol of gene expression in development.
Explain extrinsic stem cell regulatory mechanisms and the roleof niches

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Answer Differential Gene ExpressionIf the genome is the same in all somatic cells within anorganism with the exception of the abovementioned lymphocyteshow do the cells become different from one another If every cellin the body contains the genes for hemoglobin and insulin proteinshow are the hemoglobin proteins made only in the red blood cellsthe insulin proteins made only in certain pancreas cells andneither made in the kidney or nervous system Based on theembryological evidence for genomic equivalence and on bacterialmodels of gene regulation a consensus emerged in the 1960s thatcells differentiate through differential gene expression The threepostulates of differential gene expression are as follows1Every cell nucleus contains the complete genome established inthe fertilized egg In molecular terms the DNAs of alldifferentiated cells are identical2The unused genes in differentiated cells are not destroyed ormutated and they retain the potential for being expressed3Only a small percentage of the genome is expressed in each celland a portion of the RNA synthesized in the cell is specific forthat cell typeThe first two postulates have already been discussed The thirdpostulatethat only a small portion of the genome is active inmaking tissuespecific productswas first tested in insect larvaeFruit fly larvae have certain cells whose chromosomes See Answer

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