Clinical trial (a) There are several methods to assign treatments to patients in comparative clinical trials. Commonly...

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Clinical trial
(a) There are several methods to assign treatments to patientsin comparative clinical trials. Commonly used methods include purerandomization ,permutted blocks and within strata.
Briefly describe each of these technique for which theinstitution ,the sex,and age of the patient (under 50 years of ageversus over 50 years of age) are factors that could be taken intoaccount at the time of randomization.

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Stratified Randomisation refers to the situation in which strata are constructed based on values of prognostic variables and a randomisation scheme is performed separately within each stratum For example suppose that there are two prognostic variables age and gender such that four strata are constructed Treatment A Treatment B Male Age50 36 37 Female Age50 40 40 The strata size usually vary maybe there are relatively See Answer

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