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CF carrier frequency estimations in American Hispanic populations • Carrier screening kits for Cystic Fibrosis alleles have...

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Biology

CF carrier frequency estimations in American Hispanicpopulations • Carrier screening kits for Cystic Fibrosis alleleshave been updated to include more probes (CFTR 60 kit 2) • It isreported to have a detection rate of 83.7% in Hispanic Americanpopulations.

The same group have a CF incidence of 1 in 9,500. Given theabove, determine:

1) CF carrier frequency in the Hispanic American population.

2) Estimate the probability of being a carrier if a CFTR 60 kitresult is negative for a member of this population.

3) Estimate probability of a child with CF being born if oneparent is a known CF carrier and the other is Hispanic and found tobe negative when tested with the CFTR 60 kit.

Answer & Explanation Solved by verified expert
3.6 Ratings (323 Votes)
1Frequency of CF carrierindividual in the Hispanic American population is 1982Probability of being    See Answer
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