Case 1
A hard working 38-year-old women who is working as amarathon coach for 15 years has been having mild dull ache at theback of her right ankle for the past 14 months but for the past fewweeks the pain has become unbearable when she is training andexperience an excruciating pain at the back of his right leg upt oto her ankle. She has been limping on the right foot since, andexperiences frequent throbbing at the sore region. She goes to adoctor and been advised to use an anti-inflammatory drug known ascortisone, which have been helpful in reducing pain temporarily.Based on the case given,
1. What connective tissue disease does the women issuffering?
2. What causes the disease?
3– 4. What are the other possible locations in the body wherethis disease could be seen?
5. What cell normally repairs this kind of condition?
Case 2
A 44-year old patient presented in our clinic withongoing shoulder and arm pain for 3 years. He had noticed apainless tumor with feeling of pressure in his upper right arm forsome months. Clinical examination showed a painless tumor on theright upper arm, starting lateral to the axillary fold expandingabout 10 cm distally. Pathology showed multi vacuolated, granularcytoplasm with small central nuclei.
1. What structure is described by the histopathologic findingson the patients?
2. Which of the two types of adipose tissue are highlyvascularized? Why?
3. How does the adipose cells of babies react to coldtemperatures?
4. Which gene is uniquely expressed by fetal fat?