Cancer cells grow uncontrollably and do not die. Do you think that the following defect would...

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Biology

Cancer cells grow uncontrollably and do not die. Do you thinkthat the following defect would lead to a cancerous cellphenotype?Â Â
\"A gain of function mutation in growth factor signaling pathwayRTK that causes constitutive (constant) kinase activity\"
\"A p53 protein that cannot be imported into the nucleus.\"

\"A deletion of the polyadenylation signal sequence in the gene ofgrowth factor signaling pathway protein TFa.\"

\"A deletion in the TATA box in the promoter for the CDK inhibitorgene.\"
\"The DNA in the region of the Rb gene is highly methylated andthe histone tails are not acetylated.\"
\"A frameshift mutation early in the protein coding region in thegene for G1 cyclin.\"

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Cancer cells grow uncontrollably and do not die Do you think that the following defect would lead to a cancerous cell phenotype A gain of function mutation in growth factor signaling pathway RTK that causes constitutive constant kinase activity RTK or receptor tyrosine kinases are involved in cell grwoth and development Their signaling has to be regulated otherwise uncontrolled cell growth will result A constitutively active RTK means that it will result in uncontrolled cell growth leading See Answer

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