Briefly outline the neuroendocrine pathways mediating
“homeostatic†control of body weight, with particular emphasis on
the neural...
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Briefly outline the neuroendocrine pathways mediating“homeostatic†control of body weight, with particular emphasis onthe neural and hormonal mechanisms by which the body signalsmetabolic cues to the brain.
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Neuroendocrine pathways mediating control of body weight The brain plays a critical role in the regulation of physiological processes including energy homeostasis Central nervous circuits instantly assess and integrate peripheral metabolic endocrine and neuronal signals and coordinate a response that modulates both behavioral patterns and peripheral metabolism according to acute and chronic requirements The brain directs coordinates and integrates circulating hormones and metabolites that signal energy availability As a consequence it modifies energy intake and expenditure to match energy demands on an ongoing homeostatic basis establishing a metabolic setpoint Changes in body weight reflect respective changes in energy balance resulting from an imbalance between energy taken up food intake and energy expended for locomotor activity basal metabolism and thermogenesis Therefore
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