Bower is a 3 year old male English Pointer who presented withweakness ...

Bower is a 3-year â€“old male English Pointer who presented with weakness and difficulty rising. He...

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Medical Sciences

Bower is a 3-year â€“old male English Pointer who presented withweakness and difficulty rising. He also recently developed a veryred and sore area across the top of his nose. Bover had a slightfever, significant muscle atrophy, enlarged peripheral lymph nodesand an erythematous lesion on the dorsum of his nose.
He had an increased plasma protein concentration (8.0 g/dL), ahigh white blood cell count (18 X 10³ /ul), high numbersof neutrophils within joint fluids (no microorganisms cultured)consistent with immune-mediate inflammation. An antinuclearantibody (ANA) test was performed with a titer of 640 (positive isgreater than 100). Antigen-antibody complexes (anti-C3 andanti-IgG) were also observed at the dermal-epidermal junctions ofBowerâ€™s nasal lesion.
What is the diagnosis? Explain your reasoning (4 pts)
What is the treatment (2 pts)
Describe the pathogenesis of this immunological disease (4pts)

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3.7 Ratings (413 Votes)

1 ANSWER The probable diagnosis is Systemic lupus erythromatosus It is an autoimmune condition 2 ANSWER Reasons for SLE are presence of sore area across the top of the nose which is See Answer

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