BioChemistry Problem State whether the Hill Coefficient (N) is positive or negative? Explain your reasoning in each...

50.1K

Verified Solution

Question

Biology

BioChemistry Problem

State whether the Hill Coefficient (N) is positive or negative?Explain your reasoning in each case.

(a) The protein has multiple subunits, each with a singleligand-binding site. Binding of ligand to one site increases thebinding affinity of other sites for the ligand.

(b) The protein is a single polypeptide with two ligand-bindingsites, site one causes a structural change that decreases affinityfor the second ligand.

(c) A molecule binds to a protein and inhibits binding of thenatural ligand.

(d) The protein has two subunits and as one ligand binds, thesecond binds with lower affinity.

Answer & Explanation Solved by verified expert
3.7 Ratings (457 Votes)
Hill coefficient It is a measurement of cooperativity ofsubstrate binding to the protein    See Answer
Get Answers to Unlimited Questions

Join us to gain access to millions of questions and expert answers. Enjoy exclusive benefits tailored just for you!

Membership Benefits:
  • Unlimited Question Access with detailed Answers
  • Zin AI - 3 Million Words
  • 10 Dall-E 3 Images
  • 20 Plot Generations
  • Conversation with Dialogue Memory
  • No Ads, Ever!
  • Access to Our Best AI Platform: Flex AI - Your personal assistant for all your inquiries!
Become a Member

Other questions asked by students