(biochem) refering to the paper \"A safer poppy\" by Jenny Rood. It was published in The Scientist, January...

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Biology

(biochem)
refering to the paper
\"A safer poppy\" by Jenny Rood. It was published in TheScientist, January 2018, vol. 31, 1, page 61. You can access thisjournal/magazine, for free, at the
www.the-scientist.com
What makes opioid drugs \"double-edged\" swords? Can the two sidesof opioid drugs be separated? Why is the effort worth working onit?
In what directions research on receptors is going trying tosolve the crisis? Are there several strategies?
Discuss strategies for finding safer alternatives to opioids:from target point of view and/or mechanism point of view.
Are there safer pain killer commercially available?
Give a nut-shell statement about the research in this field atthe present.

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4.4 Ratings (938 Votes)

1Usually opoids acts by blocking the mudeltakappanociceptinzotin receptors mu pain receptors that are located predominantly in the central nervous system either by partialcomplete AGONIST or ANTAGONISTIC activityBy blocking mu reeptors in CNS it causes 2 effects on one hand it causesREDUCTION IN PAIN AND RELIEF on other hand it causesEUPHORIC EFFECTSTOLERANCEDEPENDENCE and ADDICTION This bimodal effect is termed as DOUBLE EDGE SWORD which is best described as depending on drug for euphoric effects rather than analgesic effectThe See Answer

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