best areas to get credible informationis from PubMed.

Sally, a 60 yr-oldfemale has been diagnosed with an autoimmune thyroid disordercalled Hashimoto’s thyroiditis. Sallyshowed up in the clinic for her Hashimoto’s today. She is currentlytaking no medications.

1.What is the difference between“signs & symptoms”?

2.What signs and symptoms wouldyou expect Sally to tell you she is experiencing?

3.What type of disorder is thisrelated to? (Highthyroid hormone or low)? Whatis the actual term?

4.Explain the feedback mechanismof thyroid hormone. Start by identifying the different structuresthat are involved in the brain and the periphery. What substances(hormones) are released in response to each of these?

5.In the individual with“Hashimoto’s Thyroiditis” what would you expect the labs to showrelative the following hormones? T3,T4, TSH, TRH?

6.Which of the thyroid hormonesis considered “active hormone” and which is considered “inactivehormone”?

7.Explain why TSH is increasedin hypothyroidism.

8.What medication is used totreat Hashimoto’s? What is its mechanism of action?

9.Are there any foods that canbe eaten (or avoided) for individuals withHashimoto’s?

10.There are some nutrients andmetals that are required cofactors for the production of thyroidhormone. If you had to design a supplement that would optimizeSally’s production of hormones, what kinds of things would you putin it?

11.If someone takes too much oftheir medication, what signs and symptoms will they exhibit? Whatcondition is this similar to?

12.What is meant by subclinicalhypothyroidism? Why is this difficult to treat?

13.Imagine someone is not takingmedication and they have been diagnosed withHashimoto’s. Why might they sometimes exhibit signs and symptoms ofhyperthyroidism as well as hypothyroidism?

14.Hashimoto’s is an autoimmunedisease. What is an autoimmune disease and how do you know this isan autoimmune disease?

15.What antibodies would youexpect to see in Hashimoto’s?