Benzodiazepines are positive allosteric modulators at the GABA-A
receptor.
a) Describe how positive allosteric modulators affect receptor
function....
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Benzodiazepines are positive allosteric modulators at the GABA-Areceptor.
a) Describe how positive allosteric modulators affect receptorfunction.
b) Discuss the mechanism of action of benzodiazepines and theireffect on central nervous system (CNS) activity.
c) GABA is also an agonist at GABA-B receptors, which are Gprotein coupled receptors that couple to Gi. Explain the signallingpathways that will be activated when GABA binds to the GABA-Breceptor.
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a Allosteric modulators are group of substance that bind to the receptors to change the receptor response to the stimuliBenzodiazepines like diazepam are positive allosteric modulators at GABAAthey
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