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B cells are activated by CD4 TH2 cells only if both cell types recognize the same...

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Biology

B cells are activated by CD4 TH2 cells only if both cell typesrecognize the same antigen. The same epitope, however, does notneed to be shared for recognition.

1. Discuss why this characteristic is important in vaccinedesign.

2. Provide an example of a conjugate vaccine used to stimulatethe synthesis of IgG antibody against Haemophilusinfluenzae B polysaccharide.

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Answer1 This phenomenon is referred to as linked recognition and is applied widely in designing vaccines like that used to immunize infants against Haemophilus influenzae type B Generation of T cell memory is fundamental in designing such vaccines which offer longterm protection against seasonal and pandemic viruses The reason for this is basically the ability of these cells to generate secondary immune    See Answer
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