At the end of the semester we discussed DNA damage and repairsystems. Then we read some papers on gene editing tools becausethese tools depend on DNA repair mechanisms in the cell to completethe editing process. For one of the three majorediting tools, ZNFs (Zinc finger nucleases), TALENS (transcriptionactivator-like effector nucleases) or CRISPR Cas9 answer thefollowing:
     i. What are the components of the geneediting system? (2 pts)
           (typeanswer here)

    ii. What are the invivo or normal functions components of the geneediting system? (2 pts)
           (typeanswer here)

    iii. What are the steps in use of the geneediting system to introduce a double stranded DNA break in thetarget DNA? If you include figures to help you answer this questionbe sure to insert in this section with your typed answer. (3pts)
           (typeanswer and insert figure here)

     iv. What are the steps in the cell’srepair system(s) and how does this participate with these geneediting systems, leading to the edited DNA? If you include a figureto help you answer this question be sure to insert in this sectionwith your typed answer. (3 pts)
           (typeanswer and insert figure here)

     v. How are the components of the geneediting system introduced to or inserted into cells? (2 pts)
           (typeanswer here)

     vi. Give a specific example of use ofthis gene editing system in attempt to correct the error(s) of aninborn error of metabolism. Describe how this was used to edit DNAto alleviate a defect and identify whether this was an in vivo, invitro or ex vivo application and if successful (2 pts).  
       (type answer here)

References used to answer the parts of this question