Assignment #10 Chapters 11 & 12

1. The mother of a child who was just diagnosed with type 1diabetes turns to the child’s father and says, “This is all yourfault. Your father has type 2 diabetes.” Is she correct in herassumption that the child inherited diabetes from his father’sfamily? Explain your response

2. Why sickle cell disease/trait and cystic fibrosis areconsidered probable genetic evolutionary disorders?

3. Why is carrier status for Duchenne muscular dystrophy (DMD)usually not transmitted from affected fathers to daughters, eventhough this disorder has an X-linked transmission pattern

4. Why is there such a high rate of spontaneous mutation amongthe genes responsible for classic hemophilia, Duchenne musculardystrophy, and achondroplasia? 5. Edward has diabetes mellitus type2 (DM type 2).He is struggling to maintain his blood sugar withinnormal limits. Edward also suffers from obesity and has been unableto control his weight with diet and exercise. He asks you if hisproblem is due to genetics. He points out that his mother also hadtype 2 diabetes and was obese. He also asks why his identical twinbrother, Edgar, does not have diabetes even though they share genesand grew up in the same environment.

A. What would you tell Edward about the genetics of DM type2?

B. What will you tell Edward about the relationship between DMtype 2 and obesity? What will you tell Edward about therelationship between DM type 2 and obesity?

C. What do you think about genetic testing for DM type 2 inyoung? Is this likely to be successful at identifying a geneticcause?

D. Would genetic counseling benefit Edward and his family?