Assess the use genetic mutant analysis and reporter genes (green fluorescent protein) tools in the study...

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Biology

Assess the use genetic mutant analysis and reporter genes (greenfluorescent protein) tools in the study of the of development. Whatare the advantages of these tools? Do they have any limitations orrestrictions?

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use of genetic mutant analysis Genetic disorders are traditionally categorized into three main groups singlegene chromosomal and multifactorial disorders Single gene or Mendelian disorders result from errors in DNA sequence of a gene and include autosomal dominant AD autosomal recessive AR Xlinked recessive XR Xlinked dominant and Ylinked holandric disorders Chromosomal disorders are due to chromosomal aberrations including numerical and structural damages Molecular and cytogenetic techniques have been applied to identify genetic mutations leading to diseases Accurate diagnosis of diseases is essential for appropriate treatment of patients genetic counseling and prevention strategies Characteristic features of patterns of inheritance are briefly reviewed and a short description of chromosomal disorders is also presented In addition applications of cytogenetic and molecular techniques and different types of mutations are discussed for genetic diagnosis of the pediatric genetic diseases use of reporter genes Reporter genes such as galactosidase and luciferase have played vital roles in the understanding of the molecular mechanisms of gene expressionThese reporter genes also have provided important information in the design of delivery systems in gene transfer into somatic tissue However See Answer

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