Answer the following questions based on this codingstrand of DNA:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â 5â€™ GGCCATGACAGAGGAGCAAAAGTTATTGCT 3â€™ Drennan et al. (1996) identified several...

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Biology

Answer the following questions based on this codingstrand ofDNA:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â
Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â 5â€™GGCCATGACAGAGGAGCAAAAGTTATTGCT 3â€™
Drennan et al. (1996) identified several mutations in thisenzyme that result in methylmalonic acidemia (MMA). One of thosemutations is a C to A at base pair 1904 in the coding strand of DNA(bold and italicized in the template strand).
Write the unique coding strand of DNA for this patient andhighlight the change you made. Write it 5â€™ to 3â€™.
Write the mRNA sequence for this patient and clearly highlightthe change you made. Write it 5â€™ to 3â€™.
Write the amino acid sequence for this patient, highlight whatdiffers from the normal (wildtype) sequence.
What type of mutation is this? (insertion, deletion, silent,nonsense,missense,or frameshift mutation? Explain yourreasoning.

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Answer According to the given question Here we have a coding strand of DNA 5 GGCCATGACAGAGGAGCAAAAGTTATTGCT 3 complementary strand is 3 CCGGTACTGTCTCCTCGTTTTCAATAACGA 5 mRNA 5 GGCCAUGACAGAGGAGCAAAAGUUAUUGCU 3 Amino acid sequenceNterminal Gly His Asp Arg Gly Ala Lys Val Ile Ala C Terminal When there is mutations in DNA coding strand See Answer

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