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AMP-PNP is the abbreviation for a structural analogue of ATP in which the second and...

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Biology

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AMP-PNP is the abbreviation for a structural analogue of ATP in which the second and third phosphate groups are linked by an NH group (instead of an oxygen atom). AMP-PNP can bind to the ATP-binding site of most ATPases (enzymes that hydrolyze ATP to ADP + P). AMP-PNP differs from ATP in that the terminal phosphate cannot be removed by hydrolysis (so you cannot create ADP, therefore, you cannot get energy from AMP-PNP). Based on this information, explain the following: a) When isolated myofibrils are placed in a flask containing Ca+ and AMP-PNP, contraction is quickly stopped. Where in the contraction cycle will contraction stop? Be specific.

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