Although mutations in the coding region of a genes can lead to changes in protein sequence...

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Biology

Although mutations in the coding region of a genes can lead tochanges in protein sequence (non-synonomous, nonsense, frameshift)there are plenty of mutations in non-coding regions within thegenome that can alter how gene are expressed. In the scenariosbelow, please indicate what non-coding regions might contain a SNP(Single Nucleotide Polymorphism) mutation, and how this SNPmutation might lead to the given scenario: a. no transcriptionoccurs for a particular gene b. Transcription occurs, but the mRNAis shorter than normal (by 100 bp) c. Transcription occurs, but themRNA is longer than normal (100 bp longer)

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A singlenucleotide polymorphism SNP is a mutation in the DNA sequence that occurs when a single nucleotide A T G or C differs between members of a species or paired chromosomes in an individual Ps can occur in coding noncoding and intergenic regions of the genome Nearly 90 SNPs occur in noncoding regions RNAs introns promoters and other control sequences repeated sequences and retroviruses are included in noncoding regions Most noncoding variants are concentrated in Deoxyribonuclease I DNase I hypersensitive sites enhancer regions and See Answer

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