After the fusion of the viral and endosomal membranes, the negative-stranded genome segments of influenza virus...

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Biology

After the fusion of the viral and endosomal membranes, thenegative-stranded genome segments of influenza virus are releasedinto the cytoplasm. Describe what happens to genome segments 4, 5and 7 during the viral replication cycle (see slides 21 and 28 oflecture 32 Powerpoint presentation). You descriptions shouldinclude:

  • Where they are localized
  • How the gene products they encode are expressed, including allviral and cellular proteins that are involved
  • How each of the gene products encoded by each segment aretrafficked through the infected cell, including each of thecellular compartments involved in the trafficking
  • Where each of the gene products end up in the progenyvirions

Provide a separate description for each of the genome segments(even though some of the steps are the same for each). Yourdescriptions should be concise but should include all relevantdetails.

Genome segment 4:

Genome segment 5:

Genome segment 7

Answer & Explanation Solved by verified expert
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After the fusion of the viral and endosomal membranes the negativestranded genome segments of influenza virus are released into the cytoplasm There are eight gene segments that make up the negative singlestranded RNA of the Influenza A virus The gene segments are known as PB1 PB2 PA NP HA NA M and NS This virus is capable of packaging their segmented genomes into the progeny virions Such packaging signals of influenza virus RNAs are    See Answer
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