About utilization of fatty acids to generate ATP, which of thefollowing is INCORRECT?
a). It is first activated by ATP to form fatty acyl-CoA in thecytosol
b). Fatty acyl-CoA needs carnitine acyltransferases to translocateto mitochondria c). Each round of beta-oxidation releases 1 acetylCoA, 1 NADH and 1 NADPH
d). The translocation process is repressed by high levels ofinsulin
e). it is repressed by active fatty acid biosynthesis
16. Biosynthesis of fatty acids in mammalian hepatocytes needsNADPH. In addition to pentose pathway, which of the followingbiochemical processes can provide additional NADPH forbiosynthesis?
a) An alternative glycolytic pathway, ED pathway, generatesNADPH b) Malic enzyme-catalyzed dehydrogenation of malate
c) Dehydrogenation of pyruvate in cytosol
d) β-oxidation of fatty acids in the cytosol recovers NADPH
e) Dehydrogenate citrate in cytosol
17. Assume a type of lipase identified in adipose tissues whichcan be activated by an unknown hormone. Upon activation, itreleases fatty acids into circulation as fuel supply. Functionally,this hormone is unlikely to be:
a). glucagon b). insulin
c). epinephrine d). T3
e). T4
18. Pancreas is important for metabolism because it produces thefollowing, EXCEPT for:
a). insulin
b). glucagon c). lipases
d). thyroids e). proteases
19. Which of the following pathway in skeletal muscle will notbe stimulated by AMPK?
a). glycogenolysis
b). glycolysis
c). gluconeogenesis
d). beta-oxidation
e). krebs cycle
30. Which one is a cofactor needed for the glycogenolysis?
For questions 37-40, refer choices given below:
a). Glut1 b). Glut2 c). Glut3 d). Glut4 e). SGLT
37. The one whose cell surface localization is enhanced byinsulin signaling pathway is?
38. Which one is expressed abundantly on neuronal cells?
39. Which one has a large Km and expressed mainly in hepatocytesand pancreatic alpha/beta-cells? 40. Which one is abundantlyexpressed in red blood cells to ensure supply of glucose toerythrocytes?
