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A vaccine for Coronavirus is likely to take a longer time than imagined, because the most...

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Medical Sciences

A vaccine for Coronavirus is likely to take a longer time thanimagined, because the most obvious target of the vaccine should bethe external spike protein on the envelope of this enveloped virus.The cellular attachment protein on epithelial cells, which thevirus binds to for entry into the epithelial cell, is known to beACE2, a receptor enzyme. Explain why the production of a vaccinetargeting the coronavirus spike protein (S1), is not likely to besuccessful.

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SARSCoV2 is a positivestrand RNA virus that belongs to the group of Betacoronaviruses It has a long ORF1ab polyprotein at the 5 end and the 3end of the genome encodes 4 major structural proteins including the spike S protein nucleocapsid N protein membrane M protein and the envelope E protein SARSCoV2 binds to    See Answer
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