A proportion of the individuals in a given population exhibit a deleterious trait that is controlled...

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Biology

A proportion of the individuals in a given population exhibit adeleterious trait that is controlled by a single gene. We know thatthis gene has only two allelic variants segregating and one of themis deleterious in the homozygous condition. Heterozygousindividuals and individuals homozygous for the other variant areindistinguishable from each other and do not exhibit the trait. Thepopulation consists of 345 normal individuals and 155 affectedindividuals. The selection coefficient for the recessive homozygoteis 0.1.
a. Assuming Hardy-Weinberg equilibrium, what are the allelicfrequencies in this population?
b. What kind of selection pressure is being exerted on this geneand how will the allelic frequencies change over time (you can alsouse a figure to illustrate)?
c. We assumed that this population is in Hardy-Weinbergequilibrium. Do you believe this is an appropriate assumption forthis scenario? Justify

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Ans As given in the question that the deleterious trait is controlled by the allele of a single gene and this allele is recessive which control this trait and that is why homozygous recessive individuals are the ones who are affected and homozygous dominant and heterozygous are not affected and are indistinguishable from each other phenotypically Now for homozygous recessive the selection coefficeint is 01 and selection coefficient is equal to 1 relative fitness so for homozygous recessive individuals their relative fitness is equal to See Answer

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