A pharmacy student is testing six different drugs that target neuromuscular transmission. Predict if the following...

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Medical Sciences

A pharmacy student is testing six different drugs that targetneuromuscular transmission. Predict if the following drugs wouldincrease, decrease or not change the magnitude of the end platepotential at the neuromuscular junction.
Acetylcholinesterase inhibitor
Â Â Â Â [ Choose ]Â Â Â Â Â Â Â Â No changeÂ Â Â Â Â Â Â Â IncreaseÂ Â Â Â Â Â Â Â Decrease Â Â Â Â
Botulism toxin
Â Â Â Â [ Choose ]Â Â Â Â Â Â Â Â No changeÂ Â Â Â Â Â Â Â IncreaseÂ Â Â Â Â Â Â Â Decrease Â Â Â Â
Black widow latrotoxin
Â Â Â Â [ Choose ]Â Â Â Â Â Â Â Â No changeÂ Â Â Â Â Â Â Â IncreaseÂ Â Â Â Â Â Â Â Decrease Â Â Â Â
Antagonist of presynaptic voltage-gated Ca2+ channels
Â Â Â Â [ Choose ]Â Â Â Â Â Â Â Â No changeÂ Â Â Â Â Â Â Â IncreaseÂ Â Â Â Â Â Â Â Decrease Â Â Â Â
Antagonist of Ach receptors
Â Â Â Â [ Choose ]Â Â Â Â Â Â Â Â No changeÂ Â Â Â Â Â Â Â IncreaseÂ Â Â Â Â Â Â Â Decrease Â Â Â Â
Antagonist of sarcolemmal voltage-gated Na+ channels
[ Choose ]Â Â Â Â Â Â Â Â NochangeÂ Â Â Â Â Â Â Â IncreaseÂ Â Â Â Â Â Â Â Decrease

Answer & Explanation Solved by verified expert

4.4 Ratings (785 Votes)

1Acetylcholinesterase InhibitorsIncrease Endplate potentials Acetyl choline inhibitors are the drugs that inhibit Acetylcholinesterasewhich degrade AcetylcholineSo it increases concentration of Acetyl choline which increases levels of Acetyl choline binding to post synaptic membrane which increase Endplate See Answer

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