A mutation in the Sar1-GEF gene causes the Sar1-GEF protein to be a soluble ER protein....

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Biology

A mutation in the Sar1-GEF gene causes the Sar1-GEF protein tobe a soluble ER protein. What is the potential outcome?

a. Everything will be the same. No change.

b. Sar1-GDP will not be created.

c. COPII coated vesicles will not be created.

d. Vesicles destined for the cis-Golgi network will not be ableto fuse with its target membrane.

Could someone expain this question? for instance if its not c,why not? isn't Sar1 responsible for building COATII vesicles,thanks a lot.

Answer & Explanation Solved by verified expert
3.9 Ratings (752 Votes)
Yes Sar1 cytosolic and Sar1GEF membranebound areresponsible for building COPII coated vesicles and yes c is thecorrect answer If    See Answer
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