A mother has a germ line mutation in Toll Like Receptor 4. Will her children carry...

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Biology

A mother has a germ line mutation in Toll Like Receptor 4. Willher children carry this mutation? Will her children be affected bythis mutation? Briefly explain your reasoning. Part b. Brieflyexplain the functional importance of TLRs within the context of animmune response.

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aGermline mutations or Hereditarymutations are the genetic changes observed in a bodys reproductivecell sperm or egg that gets incorporated into the DNA of everycell in the body of the offspring These mutations are passed onfrom parents to offspringTherefore if a mother has a germline mutation in Tolllike receptor 4 the children will carry thismutationThe Children will not be affected bymutation in Tolllike receptor 4 because this mutation is notpresent in other cells of the body somatic cells Based on familystudies the risk of getting the children affected See Answer

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