. A male student that attends a 4 year College majoring in Arts and music felt...

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Biology

. A male student that attends a 4 year College majoring in Artsand music felt sick for a day with diarrhea he took some medicationand felt fine. 8 days later he had a second round of diarrhea thistime it was much worse and lasted most of the day. Again withsomewhat more medication he was fine. 5 days later he had a 3rdround of diarrhea that was much worse and included vomiting. He wasbed ridden the next day his symptoms continued with fever. 1. Whatdisease does he have? Name the causative agent. 2. How did hebecome infected with this microbe? Explain the pathogenesis of thisdisease. 3. What is the virulence factor and how would you treatthis disease? 4. How would the immune system deal with this caseand why? 5. Why Doctors could only treat the symptoms before andnot the disease and why death may result from it?

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He is suffering from Cholera The causative agent is Vibrio cholerae He must have consumed unsafe water or unsafe food most likely contaminated by human faeces bacteria Other possibility is consumption of uncooked seafood Pathogenicity Vcholerae release cholera toxin into the intestinal lumen by pistonlike molecular pumps soon after colonizing the small intestine Cholera toxin belongs to AB toxin family and has a toxigenic A subgroup and an adhesive B subgroup Each CTB monomer can have noncovalent interaction with GM1 ganglioside which See Answer

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