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A key understanding of how synapses work is that they must be able to 1. Turn...

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Biology

A key understanding of how synapses work is that theymust be able to 1. Turn a signal on, 2. Turn a signal off again.Explain why two neurons, one dopaminergic, one glutergicdemonstrate this principle in Cocaine addition. In Nicotineaddiction, the pathway is reversed, a Cholinergic neuron isfollowed by a Dopaminergic neuron. The same logic applies.Explain.

I am an addict. Which is my best excuse? 'It’s mygenes'. 'It’s my mates'. 'It’s down-regulation of my receptors'.The excuse must be accompanied by an explanation.

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Cocaine addiction is caused due to the reward system of the bodythat is induced by the dopamine neurotransmitter The dopamine is aneurotransmitter which when released from the presynaptic neuroninteracts with the post synaptic neuron receptor and induces theeuphoric effect leading to the craving of more dopamine that canlead to addiction Mechanism of cocaine addiction involves1 Activation of the D1 dopamine receptors Cocain is apsychostimulant that increases the dopamine concentration byactivating the D1 receptors stimulates the neuron ie turns on    See Answer
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