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A graduate student sets out to study the mode of inheritance of the colour of the fur coat and tail length of mice Black mice with short tails both dominant phenotypes were screened to select dihybrids to conduct a dihybrid cross F1 Black mice with short tails X F1 Black mice with short tails The results are listed here df 1 2 3 4 5 17 mice white with long tails 49 mice Black with long tails 135 mice Black with short tails 38 mice white with short tails 0 5 0 455 1 386 2 366 3 357 4 351 Probability level alpha 0 02 5 412 7 824 9 837 11 668 13 388 0 10 2 706 4 605 6 251 7 779 9 236 0 05 3 841 5 991 7 815 9 488 11 070 0 01 6 635 9 210 11 345 13 277 15 086 0 001 10 827 13 815 16 268 18 465 20 517 a Are the results of the screen consistent with mendelian ratios expected from of dihybrid F1 X F1 cross and in which there are no gene interactions Perform a chi analysis and provide your conclusion Show your work 3 marks b In your own words is the design of the experiment appropriate to make such a conclusion If yes describe how the experiment is appropriate to make such a conclusion If no describe how the experiment could be conducted to provide conclusive evidence for the genetic basis of the widow s peak phenotype 2 marks
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