A frameshift mutation caused by the insertion of a nucleotide in the mRNA with the sequence 5'...

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Aframeshift mutation caused by the insertion of a nucleotide in themRNA with the sequence 5' CAT CAT CAT CAT CAT CAT CAT CAT CATproduces an inactive protein. A second frameshift, caused by thedeletion of a second nucleotide at some position downstream of thenucleotide insertion, restores the protein function. If therestored protein product contains four amino acids residues thatdiffer from the wild-type protein, what are the maximum and minimumnumber of nucleotides between the two point mutations?

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Answer As per the question the original sequence of the mRNA which codes for a wild type of a protein is 5 CAT CAT CAT CAT CAT CAT CAT CAT CAT 3 These 9 set of nucleotide base pairs forms a codon which codes for a particular amino acid 9 in number A frameshift mutation is the one which shifts the reading frame of the codons thereby altering the proteins formed Given in the question to the above sequence See Answer

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