A clinical trial isrun to evaluate the efficacy of a new medication to relieve pain inpatients undergoing total knee replacement surgery. In the trial,patients are randomly assigned to receive either the new medicationor the standard medication. After receiving the assignedmedication, patients are asked to report their pain on a scale of0-100 with higher scores indicative of more pain. Data on theprimary outcome are shown below.

	Sample Size	Mean Pain Score	Standard Deviation ofPain Score
New Medication	60	30.31	7.52
StandardMedication	60	53.85	7.44

Because procedures canbe more complicated in older patients, the investigators areconcerned about confounding by age. For analysis, patients areclassified into two age groups, less than 65 and 65 years of ageand older. The data are shown below.

Age < 65 Years	Sample Size	Mean Pain Score	Standard Deviation ofPain Score
New Medication	40	25.30	2.46
StandardMedication	25	45.51	1.83
Total: Age < 65Years	65	33.07	10.16
Age 65+ Years	Sample Size	Mean Pain Score	Standard Deviation ofPain Score
New Medication	20	40.33	2.16
StandardMedication	35	59.80	2.49
Total: Age 65+	55	52.72	9.74

1. Is there a statistically significant difference in mean painscores between patients assigned to the new medication as comparedto the standard medication? Run the appropriate test at =0.05.(Ignore age in this analysis.)