A chemist at a pharmaceutical company is measuring equilibrium constants for reactions in which drug candidate...

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Chemistry

A chemist at a pharmaceutical company is measuring equilibriumconstants for reactions in which drug candidate molecules bind to aprotein involved in cancer. The drug molecules bind the protein ina 1:1 ratio to form a drug-protein complex. The proteinconcentration in aqueous solution at 25 âˆ˜C is 1.58Ã—10^âˆ’6M . Drug A is introduced into the protein solution at an initialconcentration of 2.00Ã—10^-6 M. Drug B is introduced intoa separate, identical protein solution at an initial concentrationof 2.00Ã—10^-6 M. At equilibrium, the drug A-proteinsolution has an A-protein complex concentration of1.00Ã—10^-6 M, and the drug B solution has a B-proteincomplex concentration of 1.40Ã—10^-6 M.
Part A: Calculate the K_c value for the A-proteinbiding reaction.
Part B: Calculate the K_c value for the B-proteinbiding reaction.
Part C: Assuming that the drug that binds more strongly will bemore effective, which drug is the better choice for furtherresearch?

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PART AReaction for drud AProtein drug A Protein drug A comlexKc Protein drug comlex Protein drug Ainitial concentration of protein 158106Minitial concentration of drug A 200106Mfinal concentration of Protein drug A See Answer

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