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A 0.01 % solution of paracetamol API was analysed by HPLC giving a peak at 4.35...

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Chemistry

A 0.01 % solution of paracetamol API was analysed by HPLC givinga peak at 4.35 minutes from a c18 5 micron column. The peak area is159785643. The peak area of a 0.05 % paracetamol standard is80045687. Calculate the % assay for paracetamol API. Do you thinkthis would comply with release specification of an active drugsubstance?

Answer & Explanation Solved by verified expert
4.2 Ratings (521 Votes)
Ans The Assay in HPLC analysis can be calculated as per the below formula Conc of StandardPeak Area of the    See Answer
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