9. The process of DNA replication creates a particular problem for replicating the ends of linear chromosomes. a)...

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Biology

9. The process of DNA replication creates aparticular problem for replicating the ends of linearchromosomes.
a) Describe why the DNA replication machinery has difficultyreplicating DNA ends.

b) Telomerase has been identified as an enzyme that can reversethe outcome of end replication.
Describe the near-universal mammalian chromosome telomere sequenceand how telomerase solves the problem of end replication.

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Answer a The eukaryotic chromosomes are linear or rodshaped and they have ends These linear ends face difficulty in replicating DNA at the ends because the DNA at the very end of the chromosome cannot be fully copied in each round of replication resulting in a slow gradual shortening of the chromosome During    See Answer
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