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  3. 7. individual c has a mutation in the proopiomelan

7. Individual C has a mutation in the proopiomelanocortin gene (POMC), resulting in the lack of...

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Biology

7. Individual C has a mutation in the proopiomelanocortin gene(POMC), resulting in the lack of functional alpha-melanocytestimulating hormone (alpha-MSH).

a) How might this mutation impact binding at the MC4receptor?

b) Phenotypically, is individual C likely to be underweight,normal weight, or overweight? Why?

Answer & Explanation Solved by verified expert
3.7 Ratings (637 Votes)
Question 7 a Proopiomelanocortin POMC is a precursor hormone peptide which when cleaved gives rise to several endogenous agonists like the alphaMSH betaMSH gammaMSH ACTH etc The alphaMSH acts as a ligand for the MC4 receptor regulating its various functions The alphaMSH is responsible for producing the skin and hair    See Answer
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