6. Specific structural features tag proteins for transport to various intracellular and extracellular destinations. Several examples were...

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Biology

6. Specific structural features tag proteins for transport tovarious intracellular and extracellular destinations. Severalexamples were described in chapter 12, including (1) the shortpeptide Lys-Asp-Glu-Leu, (2) characteristic hydrophobicmembrane-spanning domains, and (3) mannose-6-phosphate residuesattached to oligosaccharide side chains. For each structuralfeature, answer the following questions with detail:
a. Where in the cell is the tag incorporated into theprotein?
b. How does the tag ensure that the protein reaches itsdestination?
c. Where would the protein likely go if you were to remove thetag?

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4.2 Ratings (639 Votes)

a For the peptide chain the signal sequence is usually present in the Nterminal site and very rarely in the Cterminal site or middle of the peptide chain As the tag is usually present on the Nterminal site just See Answer

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