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5. A study was performed to compare the e↵ect of dietary supplementation with a low-fibre refined...

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Statistics

5. A study was performed to compare the e↵ect of dietarysupplementation with a low-fibre refined wheat product on the serumcholesterol of 20 healthy participants aged 23-49 years. Eachsubject had a cholesterol level measured at baseline and then wasrandomly assigned to receive either a high-fibre or lowfibre diet for6 weeks. A 2-week period followed during which no supplements weretaken. Participants then took the alternative supplement for a6-week period. The results are shown below:

n    Baseline    High fiber low fiberdifference(high fibre - low fibre) difference(high fibre -baseline)    difference(low fibre-baseline)

total Cholesterol(mg/dl)    20 186 +-31   172+-28 172+-25 -1    -14    -13

(-8, +7) (-21,7)    (-20,7)
(a) Does the high-fibre diet change cholesterol level from baseline?Justify your answer.


(b)Does the low-fibre diet change cholesterol level from baseline?Justify your answer.


(c)Is the change due to the high-fibre diet di↵erent from the changedue to the low-fibre diet? Justify.

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